For more than 20 years, Dr. Knapp has been working to create meaningful links between human-computer interaction, universal design, and various forms of creativity. His research on human-computer interaction has focused on the development and design of user-interfaces and software that allow both composers and performers to augment the physical control of a musical instrument with direct sensory interaction. He holds twelve patents and is the co-inventor of the BioMuse system, which enables artists to use gesture, cognition, and emotional state to interact with audio and video media.